Financial Review: Trillium Therapeutics (TRIL) vs. Mateon Therapeutics (MATN)

Mateon Therapeutics (OTCMKTS: MATN) and Trillium Therapeutics (NASDAQ:TRIL) are both small-cap medical companies, but which is the better stock? We will compare the two businesses based on the strength of their risk, profitability, analyst recommendations, institutional ownership, dividends, valuation and earnings.

Profitability

This table compares Mateon Therapeutics and Trillium Therapeutics’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Mateon Therapeutics N/A -210.82% -175.67%
Trillium Therapeutics N/A -248.39% -65.21%

Analyst Recommendations

This is a breakdown of recent recommendations for Mateon Therapeutics and Trillium Therapeutics, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mateon Therapeutics 0 1 3 0 2.75
Trillium Therapeutics 0 0 3 0 3.00

Mateon Therapeutics presently has a consensus target price of $1.75, suggesting a potential upside of 1,029.03%. Trillium Therapeutics has a consensus target price of $14.00, suggesting a potential upside of 71.78%. Given Mateon Therapeutics’ higher possible upside, equities analysts plainly believe Mateon Therapeutics is more favorable than Trillium Therapeutics.

Valuation & Earnings

This table compares Mateon Therapeutics and Trillium Therapeutics’ gross revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Mateon Therapeutics N/A N/A -$13.65 million ($0.56) -0.28
Trillium Therapeutics N/A N/A -$23.96 million ($2.57) -3.17

Trillium Therapeutics is trading at a lower price-to-earnings ratio than Mateon Therapeutics, indicating that it is currently the more affordable of the two stocks.

Institutional & Insider Ownership

45.5% of Trillium Therapeutics shares are held by institutional investors. 4.5% of Mateon Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Risk and Volatility

Mateon Therapeutics has a beta of 1.5, indicating that its stock price is 50% more volatile than the S&P 500. Comparatively, Trillium Therapeutics has a beta of 13.72, indicating that its stock price is 1,272% more volatile than the S&P 500.

Summary

Mateon Therapeutics beats Trillium Therapeutics on 6 of the 10 factors compared between the two stocks.

Mateon Therapeutics Company Profile

Mateon Therapeutics, Inc., formerly OXiGENE, Inc., is a biopharmaceutical company. The Company is focused on the development of vascular disrupting agents (VDAs) for the treatment of cancer. The Company is engaged in developing two clinical stage investigational drugs: VDAs-CA4P and OXi4503. Its lead compound is CA4P, which is also known as combretastatin A4-phosphate, fosbretabulin tromethamine, fosbretabulin and ZYBRESTAT. VDAs selectively targets the vasculature of cancer tumors and obstructs a tumor’s blood supply without disrupting the blood supply to normal tissues. VDAs are in a class of drugs called vascular targeted therapies (VTTs), which also includes anti-angiogenic agents (AAs). CA4P is a reversible tubulin binding agent that selectively targets the endothelial cells that make up the blood vessel walls in solid tumors. The Company is pursuing the development of a product candidate, OXi4503, which is a dual-mechanism VDA.

Trillium Therapeutics Company Profile

Trillium Therapeutics Inc., a clinical-stage immuno-oncology company, develops therapies for the treatment of cancer. The company’s lead program is TTI-621, a SIRPaFc fusion protein that acts a soluble decoy receptor preventing CD47 from delivering its inhibitory signal, which is in Phase I clinical trial for advanced hematologic malignancies and solid tumors therapy. Its product candidates also include TTI-622, an IgG4 SIRPaFc protein for combination therapy; bromodomain inhibitor; and epidermal growth factor receptor antagonist, which are in preclinical development stage, as well as undisclosed immuno-oncology targets that are in the discovery Phase. The company was formerly known as Stem Cell Therapeutics Corp. and changed its name to Trillium Therapeutics Inc. in June 2014. Trillium Therapeutics Inc. was founded in 2004 and is headquartered in Mississauga, Canada.

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