Proteon Therapeutics (PRTO) and Aduro BioTech (ADRO) Critical Comparison

Proteon Therapeutics (NASDAQ: PRTO) and Aduro BioTech (NASDAQ:ADRO) are both small-cap healthcare companies, but which is the better stock? We will compare the two businesses based on the strength of their valuation, dividends, risk, profitability, analyst recommendations, earnings and institutional ownership.

Analyst Recommendations

This is a summary of recent recommendations for Proteon Therapeutics and Aduro BioTech, as provided by MarketBeat.com.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Proteon Therapeutics 0 4 1 0 2.20
Aduro BioTech 0 0 8 0 3.00

Proteon Therapeutics presently has a consensus target price of $3.43, suggesting a potential upside of 85.59%. Aduro BioTech has a consensus target price of $18.50, suggesting a potential upside of 143.42%. Given Aduro BioTech’s stronger consensus rating and higher probable upside, analysts clearly believe Aduro BioTech is more favorable than Proteon Therapeutics.

Profitability

This table compares Proteon Therapeutics and Aduro BioTech’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Proteon Therapeutics N/A -105.58% -77.60%
Aduro BioTech -548.92% -39.28% -21.15%

Earnings and Valuation

This table compares Proteon Therapeutics and Aduro BioTech’s gross revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Proteon Therapeutics $2.95 million 11.05 -$28.52 million ($2.22) -0.83
Aduro BioTech $50.68 million 11.59 -$91.14 million ($1.36) -5.59

Proteon Therapeutics has higher earnings, but lower revenue than Aduro BioTech. Aduro BioTech is trading at a lower price-to-earnings ratio than Proteon Therapeutics, indicating that it is currently the more affordable of the two stocks.

Institutional & Insider Ownership

50.1% of Proteon Therapeutics shares are owned by institutional investors. Comparatively, 45.2% of Aduro BioTech shares are owned by institutional investors. 36.3% of Proteon Therapeutics shares are owned by insiders. Comparatively, 6.6% of Aduro BioTech shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Summary

Aduro BioTech beats Proteon Therapeutics on 8 of the 13 factors compared between the two stocks.

About Proteon Therapeutics

Proteon Therapeutics, Inc. is a late-stage biopharmaceutical company, which focuses on the development of pharmaceuticals to address the needs of patients with renal and vascular disease. The Company is involved in research and development activities. The Company’s product candidate, product candidate, vonapanitase, formerly PRT-201, is a recombinant human elastase that it is developing to manage vascular access failure in patients with chronic kidney disease undergoing or planning for hemodialysis, a lifesaving treatment that cannot be conducted without a functioning vascular access. The Company has completed Phase II trial of vonapanitase in patients undergoing creation of an arteriovenous fistula (AVF). The Company initiated the first of two Phase III trials, PATENCY-1, for vonapanitase in radiocephalic AVFs. Its vonapanitase product candidate is a recombinant human elastase under development as a treatment to prevent AVF and arteriovenous graft (AVG) patency loss.

About Aduro BioTech

Aduro Biotech, Inc. is an immunotherapy company, which focuses on the discovery, development and commercialization of therapies that manage the treatment of various diseases, including cancer. The Company’s product candidates from its Live, Attenuated, Double-Deleted (LADD) Listeria monocytogenes, Stimulator of Interferon Genes Pathway Activator, and B-select monoclonal antibody platforms are designed to stimulate and/or regulate innate and adaptive immune responses, either as single agents or in combination with conventional therapies, as well as other immunotherapies. Its LADD technology platform is being developed as a treatment for multiple indications, including mesothelioma, ovarian, gastric, lung and prostate cancers. Its LADD product candidate is CRS-207, which is being developed as a treatment for multiple indications, including mesothelioma, ovarian and gastric cancers. ADU-214 and ADU-741 are product candidates in development for lung and prostate cancers, respectively.

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